Single-cell RNA sequencing of human epidermis identifies Lunatic fringe as a novel regulator of the stem cell compartment

Single-cell RNA sequencing (scRNA-seq) of human skin provides a tool for validating observations from in vitro experimental models. By analyzing a published dataset of healthy adult epidermis, we confirm that the basal epidermal layer is heterogeneous, and three subpopulations of non-dividing cells...

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Veröffentlicht in:Stem cell reports 2023-11, Vol.18 (11), p.2047-2055
Hauptverfasser: Negri, Victor Augusti, Louis, Blaise, Zijl, Sebastiaan, Ganier, Clarisse, Philippeos, Christina, Ali, Shahnawaz, Reynolds, Gary, Haniffa, Muzlifah, Watt, Fiona M.
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Sprache:eng
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