A shift of paradigm: from avoiding nanoparticular complement activation in the field of nanomedicines to its exploitation in the context of vaccine development

[Display omitted] The complement system plays a central role in our innate immunity to fight pathogenic microorganisms, foreign and altered cells, or any modified molecule. Consequences of complement activation include cell lysis, release of histamines, and opsonization of foreign structures in prep...

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Veröffentlicht in:European journal of pharmaceutics and biopharmaceutics 2023-12, Vol.193, p.119-128
Hauptverfasser: Barbey, Clara, Wolf, Hannah, Wagner, Ralf, Pauly, Diana, Breunig, Miriam
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Sprache:eng
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