Stem cell-derived paracrine factors by modulated reactive oxygen species to enhance cancer immunotherapy

Herein, we present an approach for manipulating paracrine factors and signaling pathways in adipose-derived stem cells (ADSCs) to achieve highly effective tumor immunotherapy. Our method involves precise control of reactive oxygen species concentration using the CD90-maleimide-pluronic F68-chlorin e...

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Veröffentlicht in:	Journal of controlled release 2023-11, Vol.363, p.670-681
Hauptverfasser:	Park, Naeun, Kim, Kyoung Sub, Na, Kun
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis animal models Cancer immunotherapy cell growth cytotoxicity immunotherapy interleukin-6 intravenous injection irradiation melanoma pancreatic neoplasms Paracrine factors Reactive oxygen species secretion spleen Stem cells vascular endothelial growth factor receptor-2
Online-Zugang:	Volltext
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