Machine learning analysis of pretreatment skin biopsies predicts nonresponse to dupilumab in patients with eczematous dermatitis

While dupilumab has revolutionized the treatment of atopic dermatitis (AD), a subset of patients may fail to respond or worsen after dupilumab initiation. Using a retrospective cohort of 53 dupilumab responders and 17 nonresponders, we developed a logistic regression classifier to predict nonrespons...

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Veröffentlicht in:	British journal of dermatology (1951) 2023-12, Vol.190 (1), p.132-134
Hauptverfasser:	Murphy, Michael J, Hwang, Erica, Singh, Katelyn, Lee, Trinity, Cohen, Jeffrey M, Damsky, William
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies, Monoclonal, Humanized - therapeutic use Biopsy Eczema - drug therapy Humans Machine Learning Skin - pathology Treatment Outcome
Online-Zugang:	Volltext
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