Residue Effect-Guided Design: Engineering of S. Solfataricus β‑Glycosidase to Enhance Its Thermostability and Bioproduction of Ginsenoside Compound K

β-Glycosidase from Sulfolobus solfataricus (SS-BGL) is a highly effective biocatalyst for the synthesis of compound K (CK) from glycosylated protopanaxadiol ginsenosides. In order to improve the thermal stability of SS-BGL, molecular dynamics simulations were used to determine the residue-level bind...

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Veröffentlicht in:	Journal of agricultural and food chemistry 2023-11, Vol.71 (44), p.16669-16680
Hauptverfasser:	Shen, Wenfeng, Dalby, Paul A., Guo, Zheng, Li, Weina, Zhu, Chenhui, Fan, Daidi
Format:	Artikel
Sprache:	eng
Schlagworte:	Biotechnology and Biological Transformations
Online-Zugang:	Volltext
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