In vitro methods to assess 11β-hydroxysteroid dehydrogenase type 2 activity

11β-Hydroxysteroid dehydrogenase type 2 (11β-HSD2) converts active 11β-hydroxyglucocorticoids to their inactive 11-keto forms, fine-tuning the activation of mineralocorticoid and glucocorticoid receptors. 11β-HSD2 is expressed in mineralocorticoid target tissues such as renal distal tubules and cort...

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Hauptverfasser:	Kley, Manuel, Moser, Seraina O, Winter, Denise V, Odermatt, Alex
Format:	Buchkapitel
Sprache:	eng
Online-Zugang:	Volltext
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