Novel Use of Circulating Tumor DNA to Identify Muscle-invasive and Non–organ-confined Upper Tract Urothelial Carcinoma

The detection of plasma circulating tumor DNA (ctDNA) in high-risk upper tract urothelial carcinoma prior to extirpative surgery was highly predictive of muscle-invasive and non–organ-confined staging, and strongly prognostic for progression-free and overall survival. Preoperative ctDNA demonstrates...

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Veröffentlicht in:	European urology 2024-03, Vol.85 (3), p.283-292
Hauptverfasser:	Huelster, Heather L., Gould, Billie, Schiftan, Elizabeth A., Camperlengo, Lucia, Davaro, Facundo, Rose, Kyle M., Soupir, Alex C., Jia, Shidong, Zheng, Tiantian, Sexton, Wade J., Pow-Sang, Julio, Spiess, Philippe E., Daniel Grass, G., Wang, Liang, Wang, Xuefeng, Vosoughi, Aram, Necchi, Andrea, Meeks, Joshua J., Faltas, Bishoy M., Du, Pan, Li, Roger
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Carcinoma, Transitional Cell - diagnosis Carcinoma, Transitional Cell - genetics Carcinoma, Transitional Cell - surgery Circulating Tumor DNA - genetics Humans Muscles - pathology Nephroureterectomy Prognosis Retrospective Studies Staging Ureteral Neoplasms - genetics Ureteral Neoplasms - surgery Urinary Bladder Neoplasms
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