Impact of Metabolic Stress on BeWo Syncytiotrophoblast Function

During placental formation, cytotrophoblasts (CTBs) fuse into multinucleate, microvilli‐coated syncytiotrophoblasts (STBs), which contact maternal blood, mediating nutrient, metabolite, and gas exchange between mother and fetus, and providing a barrier against fetal infection. Trophoblasts remodel t...

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Veröffentlicht in:	Chembiochem : a European journal of chemical biology 2023-12, Vol.24 (24), p.e202300410-n/a
Hauptverfasser:	Rogers, Lisa M., Huggins, Marissa, Doster, Ryan S., Omage, Joel I., Gaddy, Jennifer A., Eastman, Alison, Aronoff, David M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Achievement tests Cell Line Cell morphology Cytology developmental origins of health and disease Diabetes Diabetes mellitus Electron microscopy Enzyme-linked immunosorbent assay Extracellular matrix Female Fetuses Forskolin Gas exchange Gene expression Humans Immunofluorescence Matrix metalloproteinase Matrix metalloproteinases Metabolism Metabolites Obesity Palmitic acid Phenotypes placenta Placenta - metabolism Pregnancy Progesterone Progesterone - metabolism syncytialization Syncytin Tight junctions Trophoblasts Trophoblasts - metabolism
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