Microtubule acetylation induced by oxidative stress regulates subcellular distribution of lysosomal vesicles for amyloid‐beta secretion

Excessive production and accumulation of amyloid‐beta (Aβ) in the brain are one of the hallmarks of Alzheimer's disease (AD). Although oxidative stress is known to trigger and promote the progression of AD, the molecular relationship between oxidative stress and Aβ production is not yet fully u...

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Veröffentlicht in:Journal of cellular physiology 2023-12, Vol.238 (12), p.2812-2826
Hauptverfasser: Jeong, Jangho, Kim, Ok‐Hyeon, Shim, Jaeyeoung, Keum, Seula, Hwang, Ye Eun, Song, Seongeun, Kim, Jung‐Woong, Choi, Jee‐Hye, Lee, Hyun Jung, Rhee, Sangmyung
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