Aggregation of biodegradable amphiphilic poly(succinimide- co- N-propyl aspartamide) and poly( N-dodecyl aspartamide- co- N-propyl aspartamide) in aqueous medium and its preliminary drug-released properties

Two series of biodegradable amphiphilic copolymers, poly(succinimide- co- N-propyl aspartamide) (PSI-PA) and poly( N-dodecyl aspartamide- co- N-propyl aspartamide) (PDDA-PA) were synthesized by partial and total aminolysis of polysuccinimide (PSI), respectively. PSI-PA copolymers could self-aggregat...

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Veröffentlicht in:	Polymer (Guilford) 2005-02, Vol.46 (6), p.1821-1827
Hauptverfasser:	Chen, Haoran, Xu, Wen, Chen, Tongyu, Yang, Wuli, Hu, Jianghua, Wang, Changchun
Format:	Artikel
Sprache:	eng
Schlagworte:	Applied sciences Biodegradable amphiphilic copolymers Biological and medical sciences Chemical modifications Chemical reactions and properties Exact sciences and technology General pharmacology Medical sciences Micelle-like aggregates Organic polymers Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Physicochemistry of polymers Poly(succinimide- co- N-propyl aspartamide)
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