Deciphering resveratrol's role in modulating pathological pain: From molecular mechanisms to clinical relevance

Pathological pain, a multifaceted and debilitating ailment originating from injury or post‐injury inflammation of the somatosensory system, poses a global health challenge. Despite its ubiquity, reliable therapeutic strategies remain elusive. To solve this problem, resveratrol, a naturally occurring...

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Veröffentlicht in:	Phytotherapy research 2024-01, Vol.38 (1), p.59-73
Hauptverfasser:	Wang, Biao, Jiang, Hai‐Mei, Qi, Lu‐Ming, Li, Xiang, Huang, Qun, Xie, Xin, Xia, Qing
Format:	Artikel
Sprache:	eng
Schlagworte:	1-Phosphatidylinositol 3-kinase AKT protein Analgesics bioavailability Dorsal roots Global health Immunomodulation Inflammation Ion channels Microglia Molecular modelling natural product Oxidative stress Pain pathological pain Pharmacokinetics Public health Resveratrol Sensory neurons Signal transduction Somatosensory system TOR protein toxicity Toxicology Tumor necrosis factor receptors
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