Precision medicine in monogenic inflammatory bowel disease: proposed mIBD REPORT standards

Owing to advances in genomics that enable differentiation of molecular aetiologies, patients with monogenic inflammatory bowel disease (mIBD) potentially have access to genotype-guided precision medicine. In this Expert Recommendation, we review the therapeutic research landscape of mIBD, the report...

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Veröffentlicht in:	Nature reviews. Gastroenterology & hepatology 2023-12, Vol.20 (12), p.810-828
Hauptverfasser:	Uhlig, Holm H., Booth, Claire, Cho, Judy, Dubinsky, Marla, Griffiths, Anne M., Grimbacher, Bodo, Hambleton, Sophie, Huang, Ying, Jones, Kelsey, Kammermeier, Jochen, Kanegane, Hirokazu, Koletzko, Sibylle, Kotlarz, Daniel, Klein, Christoph, Lenardo, Michael J., Lo, Bernice, McGovern, Dermot P. B., Özen, Ahmet, de Ridder, Lissy, Ruemmele, Frank, Shouval, Dror S., Snapper, Scott B., Travis, Simon P., Turner, Dan, Wilson, David C., Muise, Aleixo M.
Format:	Artikel
Sprache:	eng
Schlagworte:	631/208/2489/201 692/4020/1503/257 Biomedicine Case reports Clinical trials Decision making Expert Recommendation Gastroenterology Gene therapy Genetic screening Genotypes Hematopoietic stem cells Hepatology Humans Inflammatory bowel disease Inflammatory bowel diseases Intestine Medicine Medicine & Public Health Meta-analysis Patients Phenotypes Precision Medicine Prospective Studies Retrospective Studies Stem cell transplantation
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