Improved performance of nucleic acid-based assays for genetically diverse norovirus surveillance

Nucleic acid-based assays, such as polymerase chain reaction (PCR), that amplify and detect organism-specific genome sequences are a standard method for infectious disease surveillance. However, challenges arise for virus surveillance because of their genetic diversity. Here, we calculated the varia...

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Veröffentlicht in:	Applied and environmental microbiology 2023-10, Vol.89 (10), p.e0033123-e0033123
Hauptverfasser:	Oh, Chamteut, Zhou, Aijia, O'Brien, Kate, Schmidt, 4th, Arthur R, Geltz, Joshua, Shisler, Joanna L, Schmidt, Arthur R, Keefer, Laura, Brown, William M, Nguyen, Thanh H
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying Communicable Diseases Epidemiology Gene sequencing Genetic diversity Genomes Humans Infectious diseases Norovirus - genetics Nucleic acids Nucleotides Polymerase chain reaction Real-Time Polymerase Chain Reaction - methods Reverse Transcriptase Polymerase Chain Reaction RNA, Viral - genetics Surveillance Target detection Viruses
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