Repurposing alagebrium for diabetic foot ulcer healing: Impact on AGEs/NFκB/NOX1 signaling

Diabetic foot ulcer (DFU) is a common diabetic complication associated with disability and reduced quality of life. Available therapeutics are not sufficient to combat the spread of DFU. Here we aim to investigate the impact of alagebrium, an advanced glycation end product (AGE)-crosslink breaker, o...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	European journal of pharmacology 2023-11, Vol.959, p.176083-176083, Article 176083
Hauptverfasser:	Harb, Afnan, Elbatreek, Mahmoud H., Elshahat, Ahmed, El-Akabawy, Nadia, Barakat, Waleed, Elkomy, Nesreen MIM
Format:	Artikel
Sprache:	eng
Schlagworte:	Alagebrium ALT-711 Diabetic foot ulcer NOX1 Wound healing Wound histopathology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!