Discovery of zolinium TSG1180 as a novel agonist of transgelin-2 for treating asthma

Asthma is a complex and heterogeneous respiratory disease that causes serious social and economic burdens. Current drugs such as β2-agonists cannot fully control asthma. Our previous study found that Transgelin-2 is a potential target for treating asthmatic pulmonary resistance. Herein, we discovere...

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Veröffentlicht in:	Biomedicine & pharmacotherapy 2023-11, Vol.167, p.115556-115556, Article 115556
Hauptverfasser:	Yuan, Hong-Kai, Li, Bo, Wu, Leyun, Wang, Xue-Ling, Lv, Zhi-Ying, Liu, Zhikai, Xu, Zhijian, Lu, Jin, Chen, Cai-Tao, Yang, Yong-Qing, Zhu, Weiliang, Yin, Lei-Miao
Format:	Artikel
Sprache:	eng
Schlagworte:	Agonist Asthma Ezrin Mechanism Molecular docking Transgelin-2
Online-Zugang:	Volltext
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