Long-Term Experimental Hyperglycemia Does Not Impair Macrovascular Endothelial Barrier Integrity and Function in vitro

Hyperglycemia is a hallmark of type 2 diabetes implicated in vascular endothelial dysfunction and cardiovascular complications. Many in vitro studies identified endothelial apoptosis as an early outcome of experimentally modeled hyperglycemia emphasizing cell demise as a significant factor of vascul...

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Veröffentlicht in:	Biochemistry (Moscow) 2023-08, Vol.88 (8), p.1126-1138
Hauptverfasser:	Khapchaev, Asker Y., Antonova, Olga A., Kazakova, Olga A., Samsonov, Mikhail V., Vorotnikov, Alexander V., Shirinsky, Vladimir P.
Format:	Artikel
Sprache:	eng
Schlagworte:	Apoptosis Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Blood vessels Calcium (intracellular) Calcium ions Complications and side effects Contractility Cytology Cytoskeleton Diabetes Diabetes mellitus (non-insulin dependent) Endothelial cells Endothelium Glucose Health aspects Hyperglycemia Life Sciences Microbiology Myosin Myosin-light-chain-phosphatase Phosphorylation Umbilical vein
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