[3H]UR-JG102–A Radiolabeled Cyclic Peptide with High Affinity and Excellent Selectivity for the Neuropeptide Y Y4 Receptor

The family of human neuropeptide Y receptors (YRs) comprises four subtypes (Y1R, Y2R, Y4R, and Y5R) that are involved in the regulation of numerous physiological processes. Until now, Y4R binding studies have been predominantly performed in hypotonic sodium-free buffers using 125I-labeled derivative...

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Veröffentlicht in:	Journal of medicinal chemistry 2023-10, Vol.66 (19), p.13788-13808
Hauptverfasser:	Gleixner, Jakob, Gattor, Albert O., Humphrys, Laura J., Brunner, Thomas, Keller, Max
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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