Generation of a Cell Line Selectively Producing Functionally Active OATP1B1 Transporter

The solute carrier organic anion transporter family member, OATP1B1, is one of the most important transporter proteins, which mediate penetration of many endogenous substances and xenobiotics into hepatocytes. A model system providing expression of the functional protein is needed to assess interact...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Biochemistry (Moscow) 2023-09, Vol.88 (9), p.1267-1273
Hauptverfasser:	Kotliarova, Mariia S., Shchulkin, Aleksei V., Erokhina, Pelageya D., Mylnikov, Pavel Y., Yakusheva, Elena N., Nadolinskaia, Nonna I., Zamakhaev, Mikhail V., Goncharenko, Anna V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Atorvastatin Biochemistry Biomedical and Life Sciences Biomedicine Bioorganic Chemistry Carrier proteins Cell culture Cloning Drug interaction Drug interactions Gene expression Genetic aspects Hepatocytes Identification and classification Life Sciences Microbiology Organic anion transporting polypeptide Polypeptides Properties Protein transport Proteins Risk assessment Substrate inhibition Western blotting Xenobiotics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!