Gene Expression Profile of 3D Spheroids in Comparison with 2D Cell Cultures and Tissue Strains of Diffuse High-Grade Gliomas

The use of relevant, accessible, and easily reproducible preclinical models of diffuse gliomas is a prerequisite for the development of successful therapeutic approaches to their treatment. Here we studied the gene expression profile of 3D spheroids in a comparison with 2D cell cultures and tissue s...

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Veröffentlicht in:	Bulletin of experimental biology and medicine 2023-08, Vol.175 (4), p.576-584
Hauptverfasser:	Arutyunyan, I. V., Soboleva, A. G., Kovtunov, E. A., Kosyreva, A. M., Kudelkina, V. V., Alekseeva, A. I., Elchaninov, A. V., Jumaniyazova, E. D., Goldshtein, D. V., Bolshakova, G. B., Fatkhudinov, T. Kh
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Apoptosis Biomedical and Life Sciences Biomedicine CD44 antigen Cell Biology Cell culture Cell proliferation Development and progression DNA repair Ethylenediaminetetraacetic acid Gene expression Genes Glial cell line-derived neurotrophic factor Glioma Glioma cells Gliomas Health aspects Hypoxia Internal Medicine Laboratory Medicine O6-methylguanine-DNA methyltransferase Pathology PTEN protein S100b protein Spheroids Tissue culture Tumors Vascular endothelial growth factor
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