Sequential heterologous immunization with COVID-19 vaccines induces broader neutralizing responses against SARS-CoV-2 variants in comparison with homologous boosters

[Display omitted] The recently prevalent variants of concerns (VOCs) of SARS-CoV-2 belong to Omicron variants which display increased transmissibility and evade from immune protection generated by vaccines and/or natural infections. Better immunization strategies should be explored to induce broader...

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Veröffentlicht in:	Vaccine 2023-10, Vol.41 (45), p.6645-6653
Hauptverfasser:	Shen, Xiuli, Hao, Yanling, Wang, Shuhui, Li, Dan, Ren, Li, Zhu, Meiling, Wang, Shuo, Li, Jing, Tang, Wenqi, Fu, Yuyu, Chen, Ran, Liu, Ying, Shao, Yiming
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Antigens Avian flu B-lymphocytes COVID-19 COVID-19 infection COVID-19 vaccines evolution Evolution & development Heterologous sequential immunization Homologous boosters Homology Immunization Inactivated vaccines Laboratory animals Lymphocytes Lymphocytes T monitoring Neutralization Neutralizing Neutralizing antibody Omicron variants pandemic Pandemics Peptides Prevention SARS-CoV-2 variants Severe acute respiratory syndrome coronavirus 2 Statistical analysis T-lymphocytes Vaccines Viruses γ-Interferon
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