Modulating the optical properties of carbon dots by peptide condensates

Here, we utilized designed condensates formed by liquid-liquid phase separation (LLPS) of cationic and aromatic peptide to sequester tyrosine-based carbon dots (C-dots). The C-dots fluorescence is quenched and retrieved upon partitioning and release from condensates, allowing a spatial regulation of C-dots fluorescence which can be utilized for biosensing applications. The fluorescence of tyrosine-carbon dots is modulated by their partitioning and release from peptide condensates.