Discovery of natural multi‐targets neuraminidase inhibitor glycosides compounds against influenza A virus through network pharmacology, virtual screening, molecular dynamics simulation, and in vitro experiment

Influenza virus continually challenges both human and animal health. Moreover, influenza viruses are easy to mutate. In a certain degree, vaccines may not catch up with rapid mutant paces of viruses. Anti‐influenza drugs NIs (neuraminidase inhibitors) are one of the best choices. Therefore, based on...

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Veröffentlicht in:	Chemical biology & drug design 2024-01, Vol.103 (1), p.e14359-n/a
Hauptverfasser:	Cao, Luxi, Liu, Yaru, Ma, Bei, Yi, Bingxiang, Sun, Jiaying
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiviral Agents - pharmacology Drugs, Chinese Herbal Enzyme Inhibitors Humans influenza Influenza A virus mechanism research Molecular Docking Simulation Molecular Dynamics Simulation multi‐targets Network Pharmacology Neuraminidase neuraminidase inhibitors virtual screening
Online-Zugang:	Volltext
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