Biological Effects and Crystal X‐Ray Study of Novel Schiff Base Containing Pentafluorophenyl Hydrazine: In Vitro and in Silico Studies

A novel Schiff base namely 3,5‐di‐tert‐butyl‐6‐((2‐(perfluorophenyl)hydrazono)methyl)phenol was successfully synthesized and characterized using FT‐IR and 1H‐NMR, 13C‐NMR, and 19F‐NMR. The crystal structure analysis of the Schiff base compound was also characterized with single crystal X‐ray diffrac...

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Veröffentlicht in:	Chemistry & biodiversity 2023-11, Vol.20 (11), p.e202301132-n/a
Hauptverfasser:	Hamurcu, Fatma, Özmen, Ümmühan Özdemir, Şentürk, Ozan Sanlı, Kaya, Kerem, Adem, Sevki, Erden, Büşra Aksoy, Celebioglu, Hasan Ufuk, Erden, Yavuz, Taslimi, Parham
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibacterial activity antibacterial activity molecular docking anticancer Biological effects Carbonic anhydrase Carbonic anhydrase I Carbonic anhydrase II Cholesterol Crystal structure Cytotoxicity E coli enzyme inhibition Enzymes Hydrazine Hydrazines hydrazone Hydrazones Imines Molecular docking NMR Nuclear magnetic resonance Phenols Protons Schiff base Single crystals Structural analysis Synthesis Toxicity
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