Seamless and non-destructive monitoring of extracellular microRNAs during cardiac differentiation from human pluripotent stem cells

Monitoring cardiac differentiation and maturation from human pluripotent stem cells (hPSCs) and detecting residual undifferentiated hPSCs are indispensable for the development of cardiac regenerative therapy. MicroRNA (miRNA) is secreted from cells into the extracellular space, and its role as a bio...

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Veröffentlicht in:	Stem cell reports 2023-10, Vol.18 (10), p.1925-1939
Hauptverfasser:	Sekine, Otoya, Kanaami, Sayaka, Masumoto, Kanako, Aihara, Yuki, Morita-Umei, Yuika, Tani, Hidenori, Soma, Yusuke, Umei, Tomohiko C., Haga, Kotaro, Moriwaki, Taijun, Kawai, Yujiro, Ohno, Masatoshi, Kishino, Yoshikazu, Kanazawa, Hideaki, Fukuda, Keiichi, Ieda, Masaki, Tohyama, Shugo
Format:	Artikel
Sprache:	eng
Schlagworte:	Anti-Arrhythmia Agents Biological Transport cardiomyocytes Cardiotonic Agents Cell Differentiation - genetics differentiation human induced pluripotent stem cell Humans maturation mesoderm microRNA MicroRNAs - genetics Pluripotent Stem Cells regenerative therapy
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