Naringenin confers protection against experimental autoimmune encephalomyelitis through modulating the gut-brain axis: A multiomics analysis

Multiple sclerosis (MS) is a disease of the central nervous system that involves the immune system attacking the protective covering of nerve fibers. This disease can be influenced by both environmental and genetic factors. Evidence has highlighted the critical role of the intestinal microbiota in M...

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Veröffentlicht in:	The Journal of nutritional biochemistry 2023-12, Vol.122, p.109448-109448, Article 109448
Hauptverfasser:	Liu, Zejin, Sun, Mengyang, Jin, Chaolei, Sun, Xiaoying, Feng, Fangyu, Niu, Xinli, Wang, Bin, Zhang, Yijie, Wang, Junpeng
Format:	Artikel
Sprache:	eng
Schlagworte:	animal models Animals autoimmune diseases brain brain metabolome Brain-Gut Axis Comamonadaceae Desulfovibrionaceae diet encephalitis Encephalomyelitis, Autoimmune, Experimental - drug therapy Encephalomyelitis, Autoimmune, Experimental - prevention & control feces gene expression genes gut microbiota homeostasis immune system immunity inflammation intestinal microorganisms metabolites metabolomics Mice Multiomics Multiple Sclerosis - pathology naringenin nerve tissue RNA, Ribosomal, 16S - genetics sclerosis spinal cord
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