Versatile DNA Balances via Adjacent Base Stacking for Homogeneous Assay of Energy Parameters, Small Molecules, And Ribonuclease

Homogeneous assays often obviate any separation and washing steps, thus minimizing the risks of contamination and false positive. DNA toehold exchange is a homogeneous, reversible process whose thermodynamic properties can be finely tuned for various assay applications. However, the developed probes...

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Veröffentlicht in:	Analytical chemistry (Washington) 2023-10, Vol.95 (39), p.14643-14650
Hauptverfasser:	Hao, Huimin, Cai, Hanfen, Yang, Bin, Lou, Shuyan, Guo, Zihua, Lu, Weiyi, Tian, Zhen
Format:	Artikel
Sprache:	eng
Schlagworte:	Assaying Base stacking Contamination Deoxyribonucleic acid DNA DNA probes Ribonuclease Risk reduction Stacking Thermodynamic properties
Online-Zugang:	Volltext
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