Identification of glycogene-based prognostic signature and validation of B3GNT7 as a potential biomarker and therapeutic target in breast cancer

Background Breast cancer is the most common cancer worldwide, with the fifth highest mortality rate among all cancers and high risk of metastasis. However, potential biomarkers and molecular mechanisms underlying the stratification of breast cancer in terms of clinical outcomes remain to be investig...

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Veröffentlicht in:	Journal of cancer research and clinical oncology 2023-12, Vol.149 (19), p.16957-16969
Hauptverfasser:	Wang, Xin, Wang, Yida, Chen, Xuanming, He, Yufei, Zhou, Xunyu, Jiao, Sitong, Zhu, Zilin, Wu, Chuanfang, Bao, Jinku
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers Biomarkers, Tumor - genetics Breast cancer Breast Neoplasms - genetics Breast Neoplasms - pathology Cancer Research Cell migration Cell proliferation ErbB-2 protein Female Gene Expression Profiling Hematology Humans Immunofluorescence Internal Medicine Medical prognosis Medicine Medicine & Public Health Metastases Molecular modelling N-Acetylglucosaminyltransferases - genetics N-Acetylglucosaminyltransferases - metabolism Oncology Prognosis Therapeutic targets Transcriptome Transcriptomics
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