Quantification of observable behaviors following oral administration of oxycodone and nalfurafine in male rhesus monkeys

Recent preclinical studies have investigated the atypical kappa-opioid receptor (KOR) agonist, nalfurafine, as a co-formulary with mu-opioid receptor (MOR) agonists as a potential deterrent for misuse. However, no study has investigated effects of nalfurafine combined with a MOR agonist using an ora...

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Veröffentlicht in:	Drug and alcohol dependence 2023-11, Vol.252, p.110953, Article 110953
Hauptverfasser:	Huskinson, Sally L., Platt, Donna M., Smith, Zachary R., Doyle, William S., Zamarripa, C. Austin, Dunaway, Kristen, Prisinzano, Thomas E., Freeman, Kevin B.
Format:	Artikel
Sprache:	eng
Schlagworte:	Administration, Oral Analgesics, Opioid - pharmacology Analgesics, Opioid - therapeutic use Animals Humans Kappa-opioid agonist Macaca mulatta Male Mu-opioid agonist Observable behavior Oral administration Oxycodone - pharmacology Receptors, Opioid, kappa - agonists Rhesus monkey
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