Epithelial-fibroblast interactions in IPF: Lessons from in vitro co-culture studies

Idiopathic pulmonary fibrosis (IPF) is a progressive interstitial disease that is characterized by increased cellular proliferation and differentiation together with excessive extracellular matrix (ECM) deposition leading to buildup of scar tissue (fibrosis) and remodeling in the lungs. The activate...

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Veröffentlicht in:	Differentiation (London) 2023-11, Vol.134, p.11-19
Hauptverfasser:	Brussow, J., Feng, K., Thiam, F., Phogat, S., Osei, E.T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Cellular crosstalk Co-culture models Differentiation Epithelium Fibroblasts Fibrosis Idiopathic pulmonary fibrosis In vitro models Proliferation extracellular matrix (ECM)
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