Hypomethylation of DRD2 promotes breast cancer through the FLNA-ERK pathway

•The DRD2 expression is regulated by its promoter region upstream factors or methylation status.•Cancer cell proliferation improved the upregulation of DRD2 and decreased DRD2’s downregulation.•DRD2 plays a critical role in the FLNA-ERK signaling pathway.•DRD2 gene is hypomethylated in hormone-recep...

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Veröffentlicht in:	Cancer genetics 2023-11, Vol.278-279, p.71-78
Hauptverfasser:	Zhang, Shuoyi, Zhong, Ming, Zhu, Hongbo, You, Qinghua, Yuan, Hao, Li, Yongping
Format:	Artikel
Sprache:	eng
Schlagworte:	Breast cancer Dopamine receptor ERK pathway High-throughput Methylation
Online-Zugang:	Volltext
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