Calibrating variant curation by clinical context based on factors that influence patients’ tolerance of uncertainty

Shared decision making manages genomic uncertainty by integrating molecular and clinical uncertainties with patient values to craft a person-centered management plan. Laboratories seek genomic report consistency, agnostic to clinical context. Molecular reports often mask laboratory-managed uncertain...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Genetics in medicine 2023-12, Vol.25 (12), p.100982, Article 100982
Hauptverfasser:	Trainer, Alison H., Goode, Erin, Hoskins, Cassandra, Wheeler, Jack C.W., Best, Stephanie
Format:	Artikel
Sprache:	eng
Schlagworte:	Clinical Decision-Making Communication Decision Making Emotions Genomic implementation Genomic medicine Genomic uncertainty Humans Patient preferences Polygenic risk scores Uncertainty Variant curation
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!