Immune thrombotic thrombocytopenic purpura in older patients: Results from the Spanish TTP Registry (REPTT)

Summary Immune thrombotic thrombocytopenic purpura (iTTP) is an ultra‐rare disease that seldom occurs in the elderly. Few reports have studied the clinical course of iTTP in older patients. In this study, we have analysed the clinical characteristics at presentation and response to therapy in a seri...

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Veröffentlicht in:	British journal of haematology 2023-12, Vol.203 (5), p.860-871
Hauptverfasser:	Gómez‐Seguí, I., Francés Aracil, E., Mingot‐Castellano, M. E., Vara Pampliega, M., Goterris Viciedo, R., García Candel, F., Pascual Izquierdo, C., Río Garma, J., Guerra Domínguez, L., Vicuña Andrés, I., Garcia‐Arroba Peinado, J., Zalba Marcos, S., Vidan Estévez, J. M., González Arias, E., Campuzano Saavedra, V., García Gala, J. M., Ortega Sanchez, S., Martínez Nieto, J., Pardo Gambarte, L., Solé Rodríguez, M., Fernández‐Docampo, M., Avila Idrovo, L. F., Hernández, L., Cid, J., Rubia Comos, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	ADAMTS13 Protein Aged caplacizumab Diagnosis Hematology Humans Patients Plasma Exchange Purpura Purpura, Thrombocytopenic, Idiopathic - therapy Purpura, Thrombotic Thrombocytopenic - diagnosis Purpura, Thrombotic Thrombocytopenic - epidemiology Purpura, Thrombotic Thrombocytopenic - therapy Registries Renal function Rituximab Rituximab - therapeutic use Thrombocytopenic purpura Thrombosis - therapy Thrombotic thrombocytopenic purpura
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Zusammenfassung:	Summary Immune thrombotic thrombocytopenic purpura (iTTP) is an ultra‐rare disease that seldom occurs in the elderly. Few reports have studied the clinical course of iTTP in older patients. In this study, we have analysed the clinical characteristics at presentation and response to therapy in a series of 44 patients with iTTP ≥60 years at diagnosis from the Spanish TTP Registry and compared them with 209 patients with
ISSN:	0007-1048 1365-2141
DOI:	10.1111/bjh.19109