Single-molecule analysis of osmolyte-mediated nanomechanical unfolding behavior of a protein domain

The small organic molecules, known as osmolytes being ubiquitously present in different cell types, affect protein folding, stability and aggregation. However, it is unknown how the osmolytes affect the nanomechanical unfolding behavior of protein domain. Here, we show the osmolyte-dependent mechani...

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Veröffentlicht in:International journal of biological macromolecules 2023-12, Vol.253, p.126849-126849, Article 126849
Hauptverfasser: Bajaj, Manish, Muddassir, Mohd, Choi, Bumjoon, Singh, Priyanka, Park, Jong Bum, Singh, Surjeet, Yadav, Manisha, Kumar, Rajesh, Eom, Kilho, Sharma, Deepak
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Sprache:eng
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