Tandem bispecific CD123/CLL‐1 CAR‐T cells exhibit specific cytolytic effector functions against human acute myeloid leukaemia

Objectives The treatment of refractory and recurrent acute myeloid leukaemia (AML) is still a challenge with poor response rates and short survival times. In an attempt to solve this problem, we constructed a tandem bispecific chimeric antigen receptor (CAR) targeting CD123 and C‐type lectin‐like mo...

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Veröffentlicht in:European journal of haematology 2024-01, Vol.112 (1), p.83-93
Hauptverfasser: Wang, Xiang‐Yu, Bian, Mei‐Ru, Lin, Guo‐Qiang, Yu, Lei, Zhang, Yan‐Ming, Wu, De‐Pei
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Sprache:eng
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