The experience of diagnosis and treatment for TAFRO syndrome

Early identification, diagnosis and treatment of TAFRO syndrome are very importants. We retrospectively analysed 6 patients with TAFRO syndrome. Their clinical manifestations, treatment methods, survival and other aspects were summarized. All patients were pathologically diagnosed with Castleman’s d...

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Veröffentlicht in:Annals of hematology 2023-12, Vol.102 (12), p.3515-3520
Hauptverfasser: Wu, Xiaolong, Zhang, Xudong, Qian, Siyu, Shi, Cunzhen, Li, Xin, Feng, Xiaoyan, Zhu, Linan, Ge, Jingjing, Li, Zhaoming, Zhang, Mingzhi
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container_issue 12
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container_title Annals of hematology
container_volume 102
creator Wu, Xiaolong
Zhang, Xudong
Qian, Siyu
Shi, Cunzhen
Li, Xin
Feng, Xiaoyan
Zhu, Linan
Ge, Jingjing
Li, Zhaoming
Zhang, Mingzhi
description Early identification, diagnosis and treatment of TAFRO syndrome are very importants. We retrospectively analysed 6 patients with TAFRO syndrome. Their clinical manifestations, treatment methods, survival and other aspects were summarized. All patients were pathologically diagnosed with Castleman’s disease, with fever, an inflammatory storm state and varying degrees of anasarca. All patients received steroid therapy; four of them also received chemotherapy, and 1 received rituximab. Of the 3 patients with severe disease, only 1 patient who received the recommended dose of glucocorticoids survived. Early administration of glucocorticoids can improve the prognosis, especially in patients with severe disease, and adequate glucocorticoids are important.
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subjects Anemia
Ascites
Biopsy
Bone marrow
Edema
Fever
Hematology
Hematuria
Inflammation
Lymphatic system
Medical diagnosis
Medical prognosis
Medicine
Medicine & Public Health
Oncology
Original Article
Patients
Phosphatase
Pleural effusion
Thrombocytopenia
title The experience of diagnosis and treatment for TAFRO syndrome
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