Mass spectrometers as cryoEM grid preparation instruments

Structure determination by single-particle cryoEM has matured into a core structural biology technique. Despite many methodological advancements, most cryoEM grids are still prepared using the plunge-freezing method developed ∼40 years ago. Embedding samples in thin films and exposing them to the ai...

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Veröffentlicht in:	Current opinion in structural biology 2023-12, Vol.83, p.102699, Article 102699
Hauptverfasser:	Westphall, Michael S., Lee, Kenneth W., Salome, Austin Z., Coon, Joshua J., Grant, Timothy
Format:	Artikel
Sprache:	eng
Schlagworte:	Cryoelectron Microscopy - methods Mass Spectrometry Water - chemistry
Online-Zugang:	Volltext
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