RNA therapeutics for epilepsy: An emerging modality for drug discovery

Drug discovery in epilepsy began with the finding of potassium bromide by Sir Charles Locock in 1857. The following century witnessed the introduction of phenotypic screening tests for discovering antiseizure medications (ASMs). Despite the high success rate of developing ASMs, they have so far fail...

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Veröffentlicht in:	Epilepsia (Copenhagen) 2023-12, Vol.64 (12), p.3113-3129
Hauptverfasser:	Hansen, Stine N., Holm, Anja, Kauppinen, Sakari, Klitgaard, Henrik
Format:	Artikel
Sprache:	eng
Schlagworte:	ASO Children Circular RNA Disease resistance Drug development Drug discovery Drug resistance Epilepsy miRNA Non-coding RNA RNA medicine seizures siRNA
Online-Zugang:	Volltext
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