HDAC3‐mediated lncRNA ZFAS1 inhibited IL‐13‐induced secretion of proinflammatory cytokines in nasal epithelial cells by regulating the miR‐7‐5p/SIRT1 pathway

Allergic rhinitis (AR) is a disease that is difficult to cure and accompanies the patient's life. Proinflammatory cytokines (GM‑CSF and eotaxin) and MUC5AC are key mediators promoting AR progression. Herein, the function of lncRNA ZFAS1 in AR was investigated. Nasal epithelial cells (NECs) were...

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Veröffentlicht in:	International journal of immunogenetics 2023-12, Vol.50 (6), p.281-290
Hauptverfasser:	Zhan, Jiabin, Li, Rui, Ye, Yi, Zheng, Jing, Wang, Gang, Wu, Jinli, Wei, Xin, Zeng, Min
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergic rhinitis Cytokines Enzyme-linked immunosorbent assay Eotaxin Epithelial cells Inflammation mRNA Non-coding RNA SIRT1 protein
Online-Zugang:	Volltext
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