Adrenomedullin/FOXO3 enhances sunitinib resistance in clear cell renal cell carcinoma by inhibiting FDX1 expression and cuproptosis

Cuproptosis, a new type of copper‐induced cell death, is involved in the antitumor activity and resistance of multiple chemotherapeutic drugs. Our previous study revealed that adrenomedullin (ADM) was engaged in sunitinib resistance in clear cell renal cell carcinoma (ccRCC). However, it has yet to...

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Veröffentlicht in:	The FASEB journal 2023-10, Vol.37 (10), p.e23143-n/a
Hauptverfasser:	Wang, Xin, Jia, Jiang‐Hua, Zhang, Ming, Meng, Qing‐Song, Yan, Bo‐Wen, Ma, Zi‐Yue, Wang, Dong‐Bin
Format:	Artikel
Sprache:	eng
Schlagworte:	adrenomedullin clear cell renal cell carcinoma cuproptosis FDX1 FOXO3 sunitinib resistance
Online-Zugang:	Volltext
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