The impact of laser energy on functional outcome following Holmium Laser Enucleation of the prostate
To assess the impact of total laser energy applied, as well as enucleation efficiency on short term functional outcomes for patients treated for lower urinary tract symptoms (LUTS) with Holmium laser enucleation of the prostate (HoLEP). A retrospective analysis of 1593 consecutive patients who under...
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| Veröffentlicht in: | Urology (Ridgewood, N.J.) N.J.), 2023-12, Vol.182, p.190-195 |
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| container_title | Urology (Ridgewood, N.J.) |
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| creator | Westhofen, Thilo Buchner, Alexander Eismann, Lennert Rodler, Severin Keller, Patrick Atzler, Michael Jokisch, Friedrich Waidelich, Raphaela Stief, Armin Becker Christian G. Weinhold, Philipp |
| description | To assess the impact of total laser energy applied, as well as enucleation efficiency on short term functional outcomes for patients treated for lower urinary tract symptoms (LUTS) with Holmium laser enucleation of the prostate (HoLEP).
A retrospective analysis of 1593 consecutive patients who underwent HoLEP for LUTS due to BPO in a tertiary care centre between January 2018 and January 2021was performed. Perioperative parameters and short-term functional outcome were evaluated. Spearman’s rank correlation and linear regression analysis was applied to identify the relationship between total laser energy applied or enucleation efficiency and functional outcome (p |
| doi_str_mv | 10.1016/j.urology.2023.08.020 |
| format | Article |
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A retrospective analysis of 1593 consecutive patients who underwent HoLEP for LUTS due to BPO in a tertiary care centre between January 2018 and January 2021was performed. Perioperative parameters and short-term functional outcome were evaluated. Spearman’s rank correlation and linear regression analysis was applied to identify the relationship between total laser energy applied or enucleation efficiency and functional outcome (p<0.05).
Median weight of enucleated tissue was 65gr, median tissue retrieval percentage was 72.2% and median surgery speed was 0.8gr/min. Median laser energy applied was 48.8kJ, median enucleation efficiency was 1.4gr/kJ. No significant correlation between the total laser energy and postoperative IPSS, Qmax or PVR was found (p-range: 0. 473- 0.969). Likewise, no correlation was found between enucleation efficiency and postoperative IPSS, Qmax and PVR (p-range: 0.080- 0.932). Perioperative improvement of functional outcome (delta IPSS, delta Qmax and delta PVR) did not correlate with total laser energy applied (p-range: 0. 211 - 0.785) or with enucleation efficiency (p-range: 0.118 – 0.543). Those results were confirmed in linear regression analysis.
The results of this study reveal that functional outcome following HoLEP are not dependant on the amount of laser energy applied or enucleation efficiency. Our results should support the increased use of HoLEP as surgical treatment option for LUTS due to BPH.</description><identifier>ISSN: 0090-4295</identifier><identifier>EISSN: 1527-9995</identifier><identifier>DOI: 10.1016/j.urology.2023.08.020</identifier><identifier>PMID: 37696310</identifier><language>eng</language><publisher>United States: Elsevier Inc</publisher><subject>Holmium ; Humans ; Laser Therapy - methods ; Lasers, Solid-State - therapeutic use ; Lower Urinary Tract Symptoms - etiology ; Lower Urinary Tract Symptoms - surgery ; Male ; Prostate - surgery ; Prostatic Hyperplasia - complications ; Prostatic Hyperplasia - surgery ; Quality of Life ; Retrospective Studies ; Treatment Outcome</subject><ispartof>Urology (Ridgewood, N.J.), 2023-12, Vol.182, p.190-195</ispartof><rights>2023 Elsevier Inc.</rights><rights>Copyright © 2023 Elsevier Inc. All rights reserved.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c313t-3b06def174f35abdc50e713ebd85ebb59fb7f1acfc436a1223ae9de8b55e3f073</cites><orcidid>0000-0003-3812-5485</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/37696310$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Westhofen, Thilo</creatorcontrib><creatorcontrib>Buchner, Alexander</creatorcontrib><creatorcontrib>Eismann, Lennert</creatorcontrib><creatorcontrib>Rodler, Severin</creatorcontrib><creatorcontrib>Keller, Patrick</creatorcontrib><creatorcontrib>Atzler, Michael</creatorcontrib><creatorcontrib>Jokisch, Friedrich</creatorcontrib><creatorcontrib>Waidelich, Raphaela</creatorcontrib><creatorcontrib>Stief, Armin Becker Christian G.</creatorcontrib><creatorcontrib>Weinhold, Philipp</creatorcontrib><title>The impact of laser energy on functional outcome following Holmium Laser Enucleation of the prostate</title><title>Urology (Ridgewood, N.J.)</title><addtitle>Urology</addtitle><description>To assess the impact of total laser energy applied, as well as enucleation efficiency on short term functional outcomes for patients treated for lower urinary tract symptoms (LUTS) with Holmium laser enucleation of the prostate (HoLEP).
A retrospective analysis of 1593 consecutive patients who underwent HoLEP for LUTS due to BPO in a tertiary care centre between January 2018 and January 2021was performed. Perioperative parameters and short-term functional outcome were evaluated. Spearman’s rank correlation and linear regression analysis was applied to identify the relationship between total laser energy applied or enucleation efficiency and functional outcome (p<0.05).
Median weight of enucleated tissue was 65gr, median tissue retrieval percentage was 72.2% and median surgery speed was 0.8gr/min. Median laser energy applied was 48.8kJ, median enucleation efficiency was 1.4gr/kJ. No significant correlation between the total laser energy and postoperative IPSS, Qmax or PVR was found (p-range: 0. 473- 0.969). Likewise, no correlation was found between enucleation efficiency and postoperative IPSS, Qmax and PVR (p-range: 0.080- 0.932). Perioperative improvement of functional outcome (delta IPSS, delta Qmax and delta PVR) did not correlate with total laser energy applied (p-range: 0. 211 - 0.785) or with enucleation efficiency (p-range: 0.118 – 0.543). Those results were confirmed in linear regression analysis.
The results of this study reveal that functional outcome following HoLEP are not dependant on the amount of laser energy applied or enucleation efficiency. Our results should support the increased use of HoLEP as surgical treatment option for LUTS due to BPH.</description><subject>Holmium</subject><subject>Humans</subject><subject>Laser Therapy - methods</subject><subject>Lasers, Solid-State - therapeutic use</subject><subject>Lower Urinary Tract Symptoms - etiology</subject><subject>Lower Urinary Tract Symptoms - surgery</subject><subject>Male</subject><subject>Prostate - surgery</subject><subject>Prostatic Hyperplasia - complications</subject><subject>Prostatic Hyperplasia - surgery</subject><subject>Quality of Life</subject><subject>Retrospective Studies</subject><subject>Treatment Outcome</subject><issn>0090-4295</issn><issn>1527-9995</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkE2P0zAURS0EYkqHnwDykk0yz3HtxCuERvMlVWIzs7Yc57m4cuJiO6D--0lpYcvKm3PvfT6EfGJQM2DyZl_PKYa4O9YNNLyGroYG3pAVE01bKaXEW7ICUFBtGiWuyIec9wAgpWzfkyveSiU5gxUZnn8g9ePB2EKjo8FkTBQnTLsjjRN182SLj5MJNM7FxhGpiyHE337a0ccYRj-PdPsndDfNNqA50aemsvQeUszFFLwm75wJGT9e3jV5ub97vn2stt8fnm6_bSvLGS8V70EO6Fi7cVyYfrACsGUc-6ET2PdCub51zFhnN1wa1jTcoBqw64VA7qDla_Ll3LsM_5wxFz36bDEEM2Gcs246uWGiVYuwNRFn1C435oROH5IfTTpqBvokWO_1RbA-CdbQ6UXwkvt8mZj7EYd_qb9GF-DrGcDlo788Jp2tx8ni4BPaoofo_zPxCpW4kdo</recordid><startdate>202312</startdate><enddate>202312</enddate><creator>Westhofen, Thilo</creator><creator>Buchner, Alexander</creator><creator>Eismann, Lennert</creator><creator>Rodler, Severin</creator><creator>Keller, Patrick</creator><creator>Atzler, Michael</creator><creator>Jokisch, Friedrich</creator><creator>Waidelich, Raphaela</creator><creator>Stief, Armin Becker Christian G.</creator><creator>Weinhold, Philipp</creator><general>Elsevier Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><orcidid>https://orcid.org/0000-0003-3812-5485</orcidid></search><sort><creationdate>202312</creationdate><title>The impact of laser energy on functional outcome following Holmium Laser Enucleation of the prostate</title><author>Westhofen, Thilo ; Buchner, Alexander ; Eismann, Lennert ; Rodler, Severin ; Keller, Patrick ; Atzler, Michael ; Jokisch, Friedrich ; Waidelich, Raphaela ; Stief, Armin Becker Christian G. ; Weinhold, Philipp</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c313t-3b06def174f35abdc50e713ebd85ebb59fb7f1acfc436a1223ae9de8b55e3f073</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Holmium</topic><topic>Humans</topic><topic>Laser Therapy - methods</topic><topic>Lasers, Solid-State - therapeutic use</topic><topic>Lower Urinary Tract Symptoms - etiology</topic><topic>Lower Urinary Tract Symptoms - surgery</topic><topic>Male</topic><topic>Prostate - surgery</topic><topic>Prostatic Hyperplasia - complications</topic><topic>Prostatic Hyperplasia - surgery</topic><topic>Quality of Life</topic><topic>Retrospective Studies</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Westhofen, Thilo</creatorcontrib><creatorcontrib>Buchner, Alexander</creatorcontrib><creatorcontrib>Eismann, Lennert</creatorcontrib><creatorcontrib>Rodler, Severin</creatorcontrib><creatorcontrib>Keller, Patrick</creatorcontrib><creatorcontrib>Atzler, Michael</creatorcontrib><creatorcontrib>Jokisch, Friedrich</creatorcontrib><creatorcontrib>Waidelich, Raphaela</creatorcontrib><creatorcontrib>Stief, Armin Becker Christian G.</creatorcontrib><creatorcontrib>Weinhold, Philipp</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Urology (Ridgewood, N.J.)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Westhofen, Thilo</au><au>Buchner, Alexander</au><au>Eismann, Lennert</au><au>Rodler, Severin</au><au>Keller, Patrick</au><au>Atzler, Michael</au><au>Jokisch, Friedrich</au><au>Waidelich, Raphaela</au><au>Stief, Armin Becker Christian G.</au><au>Weinhold, Philipp</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The impact of laser energy on functional outcome following Holmium Laser Enucleation of the prostate</atitle><jtitle>Urology (Ridgewood, N.J.)</jtitle><addtitle>Urology</addtitle><date>2023-12</date><risdate>2023</risdate><volume>182</volume><spage>190</spage><epage>195</epage><pages>190-195</pages><issn>0090-4295</issn><eissn>1527-9995</eissn><abstract>To assess the impact of total laser energy applied, as well as enucleation efficiency on short term functional outcomes for patients treated for lower urinary tract symptoms (LUTS) with Holmium laser enucleation of the prostate (HoLEP).
A retrospective analysis of 1593 consecutive patients who underwent HoLEP for LUTS due to BPO in a tertiary care centre between January 2018 and January 2021was performed. Perioperative parameters and short-term functional outcome were evaluated. Spearman’s rank correlation and linear regression analysis was applied to identify the relationship between total laser energy applied or enucleation efficiency and functional outcome (p<0.05).
Median weight of enucleated tissue was 65gr, median tissue retrieval percentage was 72.2% and median surgery speed was 0.8gr/min. Median laser energy applied was 48.8kJ, median enucleation efficiency was 1.4gr/kJ. No significant correlation between the total laser energy and postoperative IPSS, Qmax or PVR was found (p-range: 0. 473- 0.969). Likewise, no correlation was found between enucleation efficiency and postoperative IPSS, Qmax and PVR (p-range: 0.080- 0.932). Perioperative improvement of functional outcome (delta IPSS, delta Qmax and delta PVR) did not correlate with total laser energy applied (p-range: 0. 211 - 0.785) or with enucleation efficiency (p-range: 0.118 – 0.543). Those results were confirmed in linear regression analysis.
The results of this study reveal that functional outcome following HoLEP are not dependant on the amount of laser energy applied or enucleation efficiency. Our results should support the increased use of HoLEP as surgical treatment option for LUTS due to BPH.</abstract><cop>United States</cop><pub>Elsevier Inc</pub><pmid>37696310</pmid><doi>10.1016/j.urology.2023.08.020</doi><tpages>6</tpages><orcidid>https://orcid.org/0000-0003-3812-5485</orcidid></addata></record> |
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| subjects | Holmium Humans Laser Therapy - methods Lasers, Solid-State - therapeutic use Lower Urinary Tract Symptoms - etiology Lower Urinary Tract Symptoms - surgery Male Prostate - surgery Prostatic Hyperplasia - complications Prostatic Hyperplasia - surgery Quality of Life Retrospective Studies Treatment Outcome |
| title | The impact of laser energy on functional outcome following Holmium Laser Enucleation of the prostate |
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