Perianal abscess in children: an evaluation of microbiological etiology and the effectiveness of antibiotics

Purpose We aimed to evaluate the demographic characteristics of children with perianal abscess, distribution of microbiological etiology, antibiotic susceptibility, and identify the effectiveness and coverage of antibiotics due to culture results. Methods A retrospective study was designed to evalua...

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Veröffentlicht in:Pediatric surgery international 2023-09, Vol.39 (1), p.272-272, Article 272
Hauptverfasser: Guner Ozenen, Gizem, Akaslan Kara, Aybuke, Ozer, Arife, Kacar, Pelin, Ergun, Deniz, Aydin, Aysenur, Genisol Ataman, Incinur, Polatdemir, Kamer, Payza, Ayse Demet, Sorguc, Yelda, Oral, Akgun, Bayram, Nuri, Devrim, Ilker
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container_end_page 272
container_issue 1
container_start_page 272
container_title Pediatric surgery international
container_volume 39
creator Guner Ozenen, Gizem
Akaslan Kara, Aybuke
Ozer, Arife
Kacar, Pelin
Ergun, Deniz
Aydin, Aysenur
Genisol Ataman, Incinur
Polatdemir, Kamer
Payza, Ayse Demet
Sorguc, Yelda
Oral, Akgun
Bayram, Nuri
Devrim, Ilker
description Purpose We aimed to evaluate the demographic characteristics of children with perianal abscess, distribution of microbiological etiology, antibiotic susceptibility, and identify the effectiveness and coverage of antibiotics due to culture results. Methods A retrospective study was designed to evaluate pediatric patients with perianal abscesses between January 2013 and December 2022. Results A total of 197 episodes in 135 patients were evaluated. The median age of the patients was 10 months (22 days–17 years). The isolated microorganisms were Gram-positive bacteria in 56 (28.4%) patients and Gram-negative bacteria in 141 (71.6%) patients. The most common isolated species was Escherichia coli ( n  = 70, 35.5%), followed by Klebsiella spp. ( n  = 48, 24.4%), Staphylococcus aureus ( n  = 37, 18.9%), and Enterobacter spp. ( n  = 9, 4.5%). Forthy-two percent ( n  = 58) of isolates were positive for extended-spectrum beta-lactamase, 8% ( n  = 11) were carbapenem-resistant in Gram-negative bacteria, and 37.5% ( n  = 21) were methicillin-resistant, 7.1% ( n  = 4) were vancomycin-resistant in Gram-positive bacteria. According to bacterial culture results, ertapenem plus glycopeptide had the highest antimicrobial coverage rate (92.3%), followed by ertapenem plus clindamycin (89.8%), ertapenem (81.7%), third-generation cephalosporin plus glycopeptide (82.2%), third-generation cephalosporin plus clindamycin (69.5%). Conclusion Ertapenem can be a good choice in the empirical treatment of perianal abscesses in children due to its high coverage rate.
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Methods A retrospective study was designed to evaluate pediatric patients with perianal abscesses between January 2013 and December 2022. Results A total of 197 episodes in 135 patients were evaluated. The median age of the patients was 10 months (22 days–17 years). The isolated microorganisms were Gram-positive bacteria in 56 (28.4%) patients and Gram-negative bacteria in 141 (71.6%) patients. The most common isolated species was Escherichia coli ( n  = 70, 35.5%), followed by Klebsiella spp. ( n  = 48, 24.4%), Staphylococcus aureus ( n  = 37, 18.9%), and Enterobacter spp. ( n  = 9, 4.5%). Forthy-two percent ( n  = 58) of isolates were positive for extended-spectrum beta-lactamase, 8% ( n  = 11) were carbapenem-resistant in Gram-negative bacteria, and 37.5% ( n  = 21) were methicillin-resistant, 7.1% ( n  = 4) were vancomycin-resistant in Gram-positive bacteria. According to bacterial culture results, ertapenem plus glycopeptide had the highest antimicrobial coverage rate (92.3%), followed by ertapenem plus clindamycin (89.8%), ertapenem (81.7%), third-generation cephalosporin plus glycopeptide (82.2%), third-generation cephalosporin plus clindamycin (69.5%). 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Methods A retrospective study was designed to evaluate pediatric patients with perianal abscesses between January 2013 and December 2022. Results A total of 197 episodes in 135 patients were evaluated. The median age of the patients was 10 months (22 days–17 years). The isolated microorganisms were Gram-positive bacteria in 56 (28.4%) patients and Gram-negative bacteria in 141 (71.6%) patients. The most common isolated species was Escherichia coli ( n  = 70, 35.5%), followed by Klebsiella spp. ( n  = 48, 24.4%), Staphylococcus aureus ( n  = 37, 18.9%), and Enterobacter spp. ( n  = 9, 4.5%). Forthy-two percent ( n  = 58) of isolates were positive for extended-spectrum beta-lactamase, 8% ( n  = 11) were carbapenem-resistant in Gram-negative bacteria, and 37.5% ( n  = 21) were methicillin-resistant, 7.1% ( n  = 4) were vancomycin-resistant in Gram-positive bacteria. 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subjects Abscess - drug therapy
Abscess - microbiology
Abscesses
Adolescent
Anti-Bacterial Agents - therapeutic use
Antibiotics
Anus Diseases
Bacteria
Child
Child, Preschool
Female
Gram-negative bacteria
Gram-positive bacteria
Gram-Positive Bacteria - drug effects
Gram-Positive Bacterial Infections - drug therapy
Humans
Infant
Male
Medicine
Medicine & Public Health
Original Article
Pediatric Surgery
Pediatrics
Retrospective Studies
Surgery
title Perianal abscess in children: an evaluation of microbiological etiology and the effectiveness of antibiotics
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