GRK2 expression and catalytic activity are essential for vasoconstrictor/ERK-stimulated arterial smooth muscle proliferation

[Display omitted] Prolonged vasoconstrictor signalling found in hypertension, increases arterial contraction, and alters vessel architecture by stimulating arterial smooth muscle cell (ASMC) growth, underpinning the development of re-stenosis lesions and vascular remodelling. Vasoconstrictors intera...

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Veröffentlicht in:	Biochemical pharmacology 2023-10, Vol.216, p.115795, Article 115795
Hauptverfasser:	Alonazi, Asma, Nash, Craig A., Wang, Chuan-Han, Christofidou, Elena, Challiss, R.A. John, Willets, Jonathon M.
Format:	Artikel
Sprache:	eng
Schlagworte:	ERK G protein-coupled receptor kinase 2 Hypertension Proliferation Vascular remodelling Vasoconstrictors
Online-Zugang:	Volltext
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