Anlotinib Attenuates Liver Fibrosis by Regulating the Transforming Growth Factor β1/Smad3 Signaling Pathway

Background Hepatic stellate cell hyperactivation is a central link in liver fibrosis development, transforming growth factor β 1 (TGF- β 1) is a key activator of HSCs. Aims This study investigated whether anlotinib attenuates CCl4 induced liver fibrosis in mice and explored its antifibrotic mechanis...

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Veröffentlicht in:	Digestive diseases and sciences 2023-11, Vol.68 (11), p.4186-4195
Hauptverfasser:	Wu, Ye-Ting, Li, Qi-Zhe, Zhao, Xue-Ke, Mu, Mao, Zou, Gao-Liang, Zhao, Wei-Feng
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal research Biochemistry Gastroenterology Growth factors Hepatology Kinases Liver Medicine Medicine & Public Health Oncology Original Article Transplant Surgery
Online-Zugang:	Volltext
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