Comparison of corneal measurements in keratoconus eyes with two swept-source-optical coherence tomography devices and a Scheimpflug device

Purpose To assess the feasibility and reliability of biometric measurements taken with the Eyestar 900 device in keratoconus eyes in comparison with those taken with the Pentacam HR and IOLMaster 700. Methods Seventy-five eyes of 75 patients with keratoconus were included. The central corneal thickn...

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Veröffentlicht in:Graefe's archive for clinical and experimental ophthalmology 2024-03, Vol.262 (3), p.891-901
Hauptverfasser: Bograd, Alexandra, Himmel, Isabelle, Pfister, Isabel B., Seiler, Theo G., Frueh, Beatrice E., Tappeiner, Christoph
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container_issue 3
container_start_page 891
container_title Graefe's archive for clinical and experimental ophthalmology
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creator Bograd, Alexandra
Himmel, Isabelle
Pfister, Isabel B.
Seiler, Theo G.
Frueh, Beatrice E.
Tappeiner, Christoph
description Purpose To assess the feasibility and reliability of biometric measurements taken with the Eyestar 900 device in keratoconus eyes in comparison with those taken with the Pentacam HR and IOLMaster 700. Methods Seventy-five eyes of 75 patients with keratoconus were included. The central corneal thickness (CCT), thinnest point of corneal thickness (TCT), axial length (AL), flat (K1) and steep (K2) anterior and posterior (Kp1, Kp2) keratometry, maximal keratometry (KMax) and anterior chamber depth (ACD) were compared between the Eyestar 900, Pentacam HR and IOLMaster 700. Reliability parameters such as the coefficient of variation (CoV) and intraclass correlation coefficient (ICC) were calculated. Pearson’s r was determined to assess the correlation between devices. Results A high repeatability (CoV  0.9) was found for all devices, led by AL, TCT, K1 and K2 (CoV 0.01–0.36%; ICC 0.994–1.00). The largest correlation between devices was found for AL (Eyestar vs. IOLMaster, r = 1.0), K1 (Eyestar vs. IOLMaster, r = 0.997) and ACD (Eyestar vs. IOLMaster, r = 0.995; Pentacam vs. IOLMaster, r = 0.987; Eyestar vs. Pentacam, r = 0.983), but there were significant differences in measured values between devices ( p  
doi_str_mv 10.1007/s00417-023-06219-6
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Methods Seventy-five eyes of 75 patients with keratoconus were included. The central corneal thickness (CCT), thinnest point of corneal thickness (TCT), axial length (AL), flat (K1) and steep (K2) anterior and posterior (Kp1, Kp2) keratometry, maximal keratometry (KMax) and anterior chamber depth (ACD) were compared between the Eyestar 900, Pentacam HR and IOLMaster 700. Reliability parameters such as the coefficient of variation (CoV) and intraclass correlation coefficient (ICC) were calculated. Pearson’s r was determined to assess the correlation between devices. Results A high repeatability (CoV &lt; 1%) and intraclass correlation (ICC &gt; 0.9) was found for all devices, led by AL, TCT, K1 and K2 (CoV 0.01–0.36%; ICC 0.994–1.00). The largest correlation between devices was found for AL (Eyestar vs. IOLMaster, r = 1.0), K1 (Eyestar vs. IOLMaster, r = 0.997) and ACD (Eyestar vs. IOLMaster, r = 0.995; Pentacam vs. IOLMaster, r = 0.987; Eyestar vs. Pentacam, r = 0.983), but there were significant differences in measured values between devices ( p  &lt; 0.001), whereas the correlation was only slightly lower (r = 0.947 to 0.994) for KMax, CCT, TCT, K2, Kp1 and Kp2. Conclusion Keratometric and axial length measurements with the Eyestar 900 were feasible and revealed a high repeatability and a good correlation to the other devices in eyes with keratoconus.</description><identifier>ISSN: 0721-832X</identifier><identifier>EISSN: 1435-702X</identifier><identifier>DOI: 10.1007/s00417-023-06219-6</identifier><identifier>PMID: 37688609</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer Berlin Heidelberg</publisher><subject>Anterior chamber ; Cornea ; Keratoconus ; Medicine ; Medicine &amp; Public Health ; Ophthalmology</subject><ispartof>Graefe's archive for clinical and experimental ophthalmology, 2024-03, Vol.262 (3), p.891-901</ispartof><rights>The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2023. corrected publication 2023. Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.</rights><rights>2023. 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Methods Seventy-five eyes of 75 patients with keratoconus were included. The central corneal thickness (CCT), thinnest point of corneal thickness (TCT), axial length (AL), flat (K1) and steep (K2) anterior and posterior (Kp1, Kp2) keratometry, maximal keratometry (KMax) and anterior chamber depth (ACD) were compared between the Eyestar 900, Pentacam HR and IOLMaster 700. Reliability parameters such as the coefficient of variation (CoV) and intraclass correlation coefficient (ICC) were calculated. Pearson’s r was determined to assess the correlation between devices. Results A high repeatability (CoV &lt; 1%) and intraclass correlation (ICC &gt; 0.9) was found for all devices, led by AL, TCT, K1 and K2 (CoV 0.01–0.36%; ICC 0.994–1.00). The largest correlation between devices was found for AL (Eyestar vs. IOLMaster, r = 1.0), K1 (Eyestar vs. IOLMaster, r = 0.997) and ACD (Eyestar vs. IOLMaster, r = 0.995; Pentacam vs. IOLMaster, r = 0.987; Eyestar vs. Pentacam, r = 0.983), but there were significant differences in measured values between devices ( p  &lt; 0.001), whereas the correlation was only slightly lower (r = 0.947 to 0.994) for KMax, CCT, TCT, K2, Kp1 and Kp2. 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Methods Seventy-five eyes of 75 patients with keratoconus were included. The central corneal thickness (CCT), thinnest point of corneal thickness (TCT), axial length (AL), flat (K1) and steep (K2) anterior and posterior (Kp1, Kp2) keratometry, maximal keratometry (KMax) and anterior chamber depth (ACD) were compared between the Eyestar 900, Pentacam HR and IOLMaster 700. Reliability parameters such as the coefficient of variation (CoV) and intraclass correlation coefficient (ICC) were calculated. Pearson’s r was determined to assess the correlation between devices. Results A high repeatability (CoV &lt; 1%) and intraclass correlation (ICC &gt; 0.9) was found for all devices, led by AL, TCT, K1 and K2 (CoV 0.01–0.36%; ICC 0.994–1.00). The largest correlation between devices was found for AL (Eyestar vs. IOLMaster, r = 1.0), K1 (Eyestar vs. IOLMaster, r = 0.997) and ACD (Eyestar vs. IOLMaster, r = 0.995; Pentacam vs. IOLMaster, r = 0.987; Eyestar vs. Pentacam, r = 0.983), but there were significant differences in measured values between devices ( p  &lt; 0.001), whereas the correlation was only slightly lower (r = 0.947 to 0.994) for KMax, CCT, TCT, K2, Kp1 and Kp2. Conclusion Keratometric and axial length measurements with the Eyestar 900 were feasible and revealed a high repeatability and a good correlation to the other devices in eyes with keratoconus.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer Berlin Heidelberg</pub><pmid>37688609</pmid><doi>10.1007/s00417-023-06219-6</doi><tpages>11</tpages><orcidid>https://orcid.org/0000-0002-4125-8599</orcidid><orcidid>https://orcid.org/0000-0001-6907-1112</orcidid></addata></record>
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subjects Anterior chamber
Cornea
Keratoconus
Medicine
Medicine & Public Health
Ophthalmology
title Comparison of corneal measurements in keratoconus eyes with two swept-source-optical coherence tomography devices and a Scheimpflug device
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