Reappraisal of mast cell leukemia based on a single institution review of 16 cases: Mast cell morphology determines clinical outcome

Reappraisal of mast cell leukemia based on a single institution review of 16 cases: Mast cell morphology determines clinical outcome

Cytologic abnormalities of atypical mast cells in mastocytosis. The mature mast cells have oval‐shaped nuclei, cytoplasmic hypogranulation and spindle‐shaped cytology. or well‐differentiated displaying a round nucleus with condensed chromatin, and abundant dense cytoplasmic granulations. Immature ma...

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Veröffentlicht in:American journal of hematology 2024-01, Vol.99 (1), p.E1-E4
Hauptverfasser: Pardanani, Animesh, Tefferi, Ayalew, Al‐Kali, Aref, Patnaik, Mrinal, Hogan, William J., Begna, Kebede, Elliott, Michelle A., Khera, Nandita, Palmer, Jeanne M., Gangat, Naseema, Orazi, Attilio, Kelemen, Katalin, Reichard, Kaaren K., Chen, Dong
Format: Artikel
Sprache:eng
Schlagworte:
Chromatin
Cytology
Hematology
Mast cell leukemia
Mast cells
Mastocytosis
Nuclei
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Zusammenfassung:Cytologic abnormalities of atypical mast cells in mastocytosis. The mature mast cells have oval‐shaped nuclei, cytoplasmic hypogranulation and spindle‐shaped cytology. or well‐differentiated displaying a round nucleus with condensed chromatin, and abundant dense cytoplasmic granulations. Immature mast cells include promastocytes and metachromatic blast‐like forms.
ISSN:0361-8609
1096-8652
1096-8652
DOI:10.1002/ajh.27089