A specific plasma amino acid profile in the Insulin2Q104del Kuma mice at the diabetic state and reversal from hyperglycemia

The metabolites in the plasma serve as potential biomarkers of disease. We previously established an early-onset diabetes mouse model, Ins2+/Q104del Kuma mice, under a severe immune-deficient (Rag-2/Jak3 double-deficient in BALB/c) background. Here, we revealed the differences in plasma amino acid p...

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Veröffentlicht in:	Biochemical and biophysical research communications 2023-10, Vol.679, p.58-65
Hauptverfasser:	Hiyoshi, Naoya, Enomoto, Takayuki, Uefune, Fumiya, Kato, Yusuke, Wu, Yumeng, Araki, Kimi, Sakano, Daisuke, Shiraki, Nobuaki, Kume, Shoen
Format:	Artikel
Sprache:	eng
Schlagworte:	Diabetes Insulin mutation Metabolite Mouse Plasma amino acid profile
Online-Zugang:	Volltext
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