The symbiotic effect of osteoinductive extracellular vesicles and mineralized microenvironment on osteogenesis

The increasing prevalence of bone‐related diseases has raised concern about the need for an osteoinductive and mechanically stronger scaffold‐based bone tissue engineering (BTE) alternative. A mineralized microenvironment, similar to the native bone microenvironment, is required in the scaffold to r...

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Veröffentlicht in:	Journal of biomedical materials research. Part A 2024-02, Vol.112 (2), p.155-166
Hauptverfasser:	Holkar, Ketki, Kale, Vaijayanti, Pethe, Prasad, Ingavle, Ganesh
Format:	Artikel
Sprache:	eng
Schlagworte:	Alkaline phosphatase Angiogenesis Bone and Bones Bone growth Bone healing Calcium Calcium - metabolism Cargo Cell Differentiation Enzymes Extracellular Vesicles hydroxyapatite Interpenetrating networks Mesenchymal stem cells Mineralization mineralized microenvironment mRNA Optimization Osteoblasts Osteoconduction Osteogenesis osteoinduction Regeneration Regeneration (physiology) Scaffolds Secretome Stem cells Tissue engineering Vesicles
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