STAP ‐2 negatively regulates BCR ‐mediated B cell activation by recruiting tyrosine‐protein kinase CSK to LYN

Although signal‐transducing adaptor protein‐2 (STAP‐2) acts in certain immune responses, its role in B cell receptor (BCR)‐mediated signals remains unknown. In this study, we have revealed that BCR‐mediated signals, cytokine production and antibody production were increased in STAP‐2 knockout (KO) m...

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Veröffentlicht in:	FEBS letters 2023-10, Vol.597 (19), p.2433-2445
Hauptverfasser:	Kashiwakura, Jun‐ichi, Kawahara, Shoya, Inagaki, Iori, Inui, Kyosuke, Saitoh, Kodai, Kagohashi, Kota, Sasaki, Yuto, Kobayashi, Fuki, Kitai, Yuichi, Muromoto, Ryuta, Oritani, Kenji, Matsuda, Tadashi
Format:	Artikel
Sprache:	eng
Online-Zugang:	Volltext
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