Customizing amino acid metabolism of Pichia pastoris for recombinant protein production

Amino acids are the building blocks of proteins. In this respect, a reciprocal effect of recombinant protein production on amino acid biosynthesis as well as the impact of the availability of free amino acids on protein production can be anticipated. In this study, the impact of engineering the amin...

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Veröffentlicht in:	Biotechnology journal 2023-12, Vol.18 (12), p.e2300033-n/a
Hauptverfasser:	Rußmayer, Hannes, Buchetics, Markus, Mattanovich, Matthias, Neubauer, Stefan, Steiger, Matthias, Graf, Alexandra B., Koellensperger, Gunda, Hann, Stephan, Sauer, Michael, Gasser, Brigitte, Mattanovich, Diethard
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acids - metabolism bioprocess engineering Bioreactors industrial biotechnology metabolic engineering Pichia - genetics Pichia - metabolism Recombinant Proteins - metabolism synthetic biology systems biology
Online-Zugang:	Volltext
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