Structural studies with crotoxin B from Crotalus durissus collilineatus venom suggest a heterodimeric assembly formed by two new isoforms

In accidents involving Crotalus snakes, the crotoxin complex (CTX) plays lethal action due to its neurotoxic activity. On the other hand, CTX have potential biotechnological application due to its anti-tumoral, anti-inflammatory, antimicrobial, analgesic and immunomodulatory properties. CTX is a het...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Biochimie 2024-03, Vol.218, p.46-56
Hauptverfasser:	Salvador, Guilherme H.M., Fernandes, Carlos A.H., Borges, Rafael J., Soares, Andreimar M., Fontes, Marcos R.M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Crotalus Crotoxin Neurotoxin Phospholipase A2 Quaternary structure X-ray crystallography
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!